Microsatellite instability & survival in patients with stage II/III colorectal carcinoma Markovic Srdjan1,5, Antic Jadranka2, Dimitrijevic Ivan3, Zogovic Branimir4, Bojic Daniela1,5, Svorcan Petar1,5, Markovic Velimir3,5 & Krivokapic Zoran2,5
نویسندگان
چکیده
Background & objectives: The two key aspects associated with the microsatellite instability (MSI) as genetic phenomenon in colorectal cancer (CRC) are better survival prognosis, and the varying response to 5-fluorouracil (5-FU)-based chemotherapy. This study was undertaken to measure the survival of surgically treated patients with stages II and III CRC based on the MSI status, the postoperative 5-FU treatment as well as clinical and histological data.
منابع مشابه
Current trends in clinical genetics of colorectal cancer.
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تاریخ انتشار 2016